MobiusHD® Technology

Amplifying the body’s natural response mechanism

MobiusHD® is an investigational endovascular implant designed to reshape the carotid sinus.

The pressure of the pulsatile wave produced with each heart beat is interpreted by the baroreceptors, or nerves located in the walls of the carotid sinus. Reshaping the carotid sinus with the MobiusHD® amplifies the blood pressure perceived by the baroreceptors. The baroreceptors then signal the brain, which responds to the perceived higher pressure by dilating the peripheral vasculature to lower overall blood pressure.

The MobiusHD® implant is available in three different sizes for vessel diameters ranging from 5 mm to 11.75 mm. The implant is placed in the carotid sinus with the windows of the device against the carotid bulb, where the carotid baroreceptors are concentrated.

The MobiusHD® system is placed in the carotid sinus using standard percutaneous interventional techniques under fluoroscopic (x-ray) guidance.

The Treatment

The MobiusHD® is a self-expanding nitinol implant that is delivered intravascularly to the internal carotid sinus via the Delivery Catheter. Using common interventional techniques, a guiding catheter and guidewire are introduced into the vasculature at the femoral artery in the groin and placed near the carotid sinus. The delivery catheter is introduced and advanced through the length of the guiding catheter over a guidewire and into the carotid sinus. Once in position, the MobiusHD® implant is deployed, and the delivery catheter, guidewire and guiding catheter are removed.

The Procedure

Through a standard groin puncture, the MobiusHD® system is placed in the carotid sinus using standard percutaneous interventional techniques under fluoroscopic (x-ray) guidance.

The system is navigated to the carotid sinus using a conventional 0.014” guidewire and 8F guide catheter or 6F sheath. Once within the sinus, the system allows for partial deployment and resheathing of the MobiusHD® implant to enable optimal placement.

The implant is released from the delivery catheter and the delivery catheter is removed.

Caution: Investigational Device. Limited by United States law to investigational use. EU: For clinical trial use only. LBL0394 Rev D

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